Profiles In Courage Essays (1665 words) - , Term Papers

Profiles In Courage Profiles In Courage, John F. Kennedy Summary The Pulitzer Prize-winning account of men of principle, integrity and bravery in American politics was here available in President John F. Kennedy's Profiles In Courage. Eight men who served the United States Government were selected by John F. Kennedy as models of virtue and courage under pressure. These eight men persevered in their pursuit of justice and the right path, in spite of the coercion and vilification of the majority. These heroes include Mississippi's Lucius Quintus Cincinnatus Lamar who stood up to unbounded calumny when he moved to reconcile Northern and Southern differences during the years after the Civil War, and George Norris, who, in 1910, crusaded against the strong and often dictatorial leadership of his own party. Others profiled by Kennedy included John Quincy Adams, Daniel Webster, Thomas Hart Benton, Sam Houston, Edmund G. Ross, and Robert A. Taft. John Kennedy's spirited words and devotion to courage lived on in this novel. A thoughtful and persuasive book about political integrity. (The New York Times) Nominated for a Grammy Award in 1991, a recording of Profiles In Courage featured John F. Kennedy, Jr., reading his father's portrait of courageous Americans. John F. Kennedy inspired one generation, and now others, to believe that politics can be a noble profession. For President Kennedy, history was not a dull, dry subject, but came alive in the stories of people who risked their careers to stand up for what was right for our country, even when it was not the easy thing to do. This distinguished belief is played out in his novel in several ways. For example, President John Quincy Adams faced political aversion from his own Federalist Party which was turning to desert him. Also, Henry Clay showed courage when he dragged himself into Senate meetings through excruciating pain and anguish due to his failing health. John F. Kennedy stated, One man can make a difference, and every man should try. (Preface p.10) Of course, this applies to everyone, including women. Many people first learned how this was true when the read this book. The leaders of the past, like Daniel Webster, Henry Clay and Edmund G. Ross, set a shining example for Americans today to live up to. Later, the John F. Kennedy Profile in Courage Award was created by his son, John F. Kennedy Jr.. to be awarded to elected officials who exemplified the kind of courage he wrote about. Interestingly, many of the stories in this book told of courage in standing up against slavery around the time of the Civil War. More than one hundred years later, the struggle for civil rights goes on. The first two Profiles in Courage Award winners, and many other courageous Americans, prove that people must never stop fighting for what they believe is right. The first recipient, Alabama Congressman Carl Elliott, fought for equal opportunity in education and was redistricted of his congressional seat in retaliation for his courageous and principled stand. The second winner, Georgia Democratic Congressman Charles Weltner, took an oath to support his party's ticket in the upcoming fall election. When segregationist Lester Maddox won the preliminary and became the Democratic nominee for Governor of Georgia, Weltner followed his conscious and resigned from politics, rather than violate his oath, or belief that segregation was wrong. Each of these men mentioned in Profiles In Courage risked their careers to do what they believed was right, and often they risked their lives. John F. Kennedy hoped that each person who read this book and learned about courageous people in public life would realize that when a person faces a difficult decision which is bound to be unpopular, they are not alone. Each person must stand up for what they believe in and be willing to take the consequences, if they wanted to make the country a better place to live. Response In Profiles In Courage, the late President John F. Kennedy, then a Massachusetts Senator, paid tribute to a number of Americans, primarily U.S. Senators, who distinguished themselves through acts of political courage. None of the subjects were portrayed as perfect or beyond reproach. Kennedy showed very strongly, in fact, the ethical ambivalence of some of the classic figures in American history in this work. The point he sought to make is not about how heroes were made of different stuff than others. This book is about how human beings can, in a time of moral crisis, find the courage to follow their own truth

Morrison essays

Morrison essays Toni Morrisons, Beloved, is a complex narrative about the love between mothers and daughters, and the agony of guilt.It is the ultimate gesture of a loving mother. It is the outrageous claim of a slave.? These are the words, of Toni Morrison, used to describe the actions of Sethe, the central character in the novel. She, a former slave, chooses to kill her baby girl rather then let her live a life in slavery. In preventing her from the physical and emotional horrors of slavery, Sethe has put herself in to a realm of physical and emotional pain: guilt. And in understanding her guilt we can start to conceive her motivations for killing her third nameless child. Did Beloveds death come out of love or selfish pride? In preventing her child from going into slavery, Sethe, too, protected herself, she prevented herself from re-entering captivity. In examining Sethes character we can see that her motivations derive from her deep love towards her children, and from the lack of love for herself. Sethes children are her only good quality. Her children are a part of her and in killing one she kills a part of herself. What hinders over Sethe is her refusal to accept responsibility for her babys death. Does she do this because she is selfishness or because it need not be justified? Sethes love is clearly displayed by sparing her daughter from a horrific life, yet, Sethe refuses to acknowledge that her show of compassion is also Throughout the work, seems to have two separate identities, which affect her actions. When reunited with Paul D., Sethe recalls her reactions to School Teachers arrival with no mention to her daughters death. Oh, no. I wasnt going back there [Sweet Home]. I went to jail instead?(42) Sethe believes she made a moral stand in not letting herself be taken into custody. In her statement she has done two things, she has disa...

11 Steps to Writing the Perfect Resume

11 Steps to Writing the Perfect Resume Whether you’re planning to use a resume-writing service or give it a go on your own, it’s important to take some time to prepare for your resume rewrite. Your resume will only be as good as the information you or your writer has work with. Gather the following details ahead of time to craft a powerful document that effectively tells your story and markets your qualifications. Contact information.While this section may seem obvious, there are a few factors to consider. For instance, how will you display your name? Are you planning to use a nickname, such as Bob, or will you use your full name for the job search? Whichever you choose, make sure you consistently represent your name on all your personal branding materials such as your business cards, LinkedIn profile, and online portfolio or blog.Select one email address and one phone number to include on your resume. I recommend setting up an email address that’s dedicated to your job-search activities and using you r cell phone number on your resume, as this gives you the ability to control the voicemail message, who answers the phone, and when.Online presence.A Jobvite social recruiting survey found that 93 percent of recruiters will search for your online profiles before they decide to interview you. Save them some time by including the URL to your LinkedIn profile. Don’t have a LinkedIn profile yet? Check out this video tutorial by Lindsey Pollak for help creating your profile.In addition to your LinkedIn account, include any links that are relevant to your work, such as a personal website, portfolio, or blog. If your work involves social media, you may include the links to other social media accounts such as Twitter, Instagram, and so forth.Sample job descriptionsA great resume is tailored to support a specific job goal. One of the best ways to ensure your resume is properly positioned is to identify sample jobs that you’re interested in and qualified to perform.Search online and gather a few job postings that represent the type of position you’re targeting. It doesn’t matter if the location is ideal; for this purpose, you should only be concerned with the job description and its requirements.Copy and paste the text of the description itself into a Word or Google document and then highlight or bold any requirements or desirable skills from the posting you possess. This will help you or your writer identify which of your qualifications should be showcased throughout the resume.Technical skills and proficienciesWhat technical platforms and tools are you proficient? List all that apply to your work. Be specific and as comprehensive as possible. This list can include anything from social media platforms to project management systems and computer languages. If you’ve worked with proprietary platforms, list those as well.Need to brush up on a skill or tool that’s routinely popping up in the job descriptions you’re targeting?   Check out edX, Coursera, and SkillShare for free or low-cost online courses.Your professional experience.Start with your most recent job and work your way backwards. You’ll need to detail out all your professional positions within the past 15 years. If you served in the military or held a board position, list this experience as you would any other role in your work history. If you recently graduated from college, include your internships and any work experience that took place since you entered college.For each role, list the following information:Company Name and URLJob Title: If your title is very specific to your organization, you can include a translation of sorts in parentheses next to your official job title.Start and End Dates: Include the month and year for each of these dates.Job Description: Think about your roles and responsibilities as they relate to your target role. This is especially important if you’d like to change careers. Include details such as how many people you managed or supervised, the territories you covered, etc.Achievements: Brainstorm a list your accomplishments and major contributions that benefited the organization during your tenure. The number of achievements you provide will depend upon how long you remained in that role and how relevant it is to your current job goals. Quantify your accomplishments whenever possible; for instance, how did you help save the company money, generate revenue, improve customer satisfaction, increase productivity, and so forth?If you have an existing resume, only include new details in this section. There’s no reason to repeat anything that already appears in your current resume.Early career historyIf you’ve been in the workforce for over 15 years, chances are you have a few positions that got left out of the previous section. Make a list of the job titles you held, the names of each employer, the locations where you worked, and your dates of employment for these rol es. While the dates will likely not get used in your resume, it’s good to have a clear record of your earlier experiences for the writer.Volunteer workHave you been actively volunteering with a non-profit organization? Skills-based volunteering (SBV) is a great way to fill an employment gap or supplement your work history when you’re trying to change careers.   Please list any volunteer work you’ve done that’s relevant to your current job goals in chronological order, beginning with your most recent work.  If you’re new to the workforce, include any campus activities or clubs in which you were active.Record the name of the organization and its website URL, the positions you held, your years of involvement, and your responsibilities and contributions to the non-profit. Looking for new volunteer opportunities?  Visit sites such as Catchafireand VolunteerMatch.Professional affiliationsList any relevant professional organizations or affiliations you’re a member of that aren’t listed on your resume. For each group, please list their name and URL, when you became a member, and any positions you’ve held. If you took an active role in the organization, describe your responsibilities and any notable achievements.Interested in joining a new association? Check out WEDDLE’s Association Directory or research which groups your peers and managers belong to. You can often find this information on their LinkedIn profiles.Language skillsLanguage skills can be a great selling point on your resume. If you’re multilingual, be sure to list each language you speak and your proficiency level.Education and professional developmentCreate a record of all your education, beginning with your most recent degree. List the institution, its location, the name of your degree, your major and minor, your graduation year, and any honors associated with the degree, such as summa or magna cum laude. Do the same for any rele vant certifications you’ve obtained or additional training opportunities or workshops you’ve attended.Third-party feedbackHave you received positive customer testimonials or a great performance review? Include this information in your preparation materials. You or your resume writer  may be able to work some of this information into your resume to demonstrate your hard and soft skills in the workplace.While this may feel like a lot of work now, by taking the time to examine your career now, you’ll see the benefits in your future resume.Note: this article was originally published on TopResume.TopResume is a Talent Inc. company, the personal branding destination for all career-driven professionals. Through our extensive network of professional writers, we offer career advice and analyze and write more resumes and LinkedIn profiles than any other service in the world. Ready to get started? Request a free resume critique today.

Bachelor's degree is helpful to increasing personal skills Research Paper

Bachelor's degree is helpful to increasing personal skills - Research Paper Example 27s+degree+is+helpful+to+increasing+personal+skills&hl=en&sa=X&ei=ZFDfU7PiDIj54QSDr4CYAg&redir_esc=y#v=onepage&q=bachelors%20degree%20is%20helpful%20to%20increasing%20personal%20skills&f=false http://books.google.co.ke/books?id=PDmMpwbs_CsC&pg=PA15&dq=bachelor%27s+degree+is+helpful+to+increasing+personal+skills&hl=en&sa=X&ei=BXXfU5vTNarB7Aaq8IG4BA&redir_esc=y#v=onepage&q=bachelors%20degree%20is%20helpful%20to%20increasing%20personal%20skills&f=false http://books.google.co.ke/books?id=dH2nB1CX2SMC&pg=PA327&dq=bachelor%27s+degree+is+helpful+to+increasing+personal+skills&hl=en&sa=X&ei=j47fU82-CLLQ7Aaw9IG4Cg&redir_esc=y#v=onepage&q=bachelors%20degree%20is%20helpful%20to%20increasing%20personal%20skills&f=false http://books.google.co.ke/books?id=AHsqIFnnn1YC&pg=PA92&dq=bachelor%27s+degree+is+helpful+to+increasing+personal+skills&hl=en&sa=X&ei=j47fU82-CLLQ7Aaw9IG4Cg&redir_esc=y#v=onepage&q=bachelors%20degree%20is%20helpful%20to%20increasing%20personal%20skills&f=false http://books.google.co.ke/books?id=xrnPJcb7c54C&pg=PA90&dq=bachelor%27s+degree+is+helpful+to+increasing+personal+skills&hl=en&sa=X&ei=n5XfU6LhAqXB7AbujYHgDQ&redir_esc=y#v=onepage&q=bachelors%20degree%20is%20helpful%20to%20increasing%20personal%20skills&f=false http://books.google.co.ke/books?id=aSiCCLKHOL0C&pg=PA138&dq=bachelor%27s+degree+is+helpful+to+increasing+personal+skills&hl=en&sa=X&ei=n5XfU6LhAqXB7AbujYHgDQ&redir_esc=y#v=onepage&q=bachelors%20degree%20is%20helpful%20to%20increasing%20personal%20skills&f=false The book gives details on the kind of training required for public health professionals. It expounds on the relevant skills required.

Careers in health care industry Essay Example | Topics and Well Written Essays - 250 words

Careers in health care industry - Essay Example Health Information and Medical Records TechnicianThey are concerned with keeping patients health information records. The Department of labor in the US estimates 20% growth in this career before 2018. To be in this field, a degree in an associate’s degree is required (Parker 1).Medical AssistantThey work directly with patients. They work on the patient’s medical history and also take their vital signs. An Associate’s degree or a certificate program are the requirements.Pharmacy TechnicianThey provide customer service and also prescribe medication to patients. Only an Associate’s degree or certificate are needed.Environmental health directorTraining environmental regulations as well as offering education concerning the government in public operations and also in private. Degree in Bachelor’s and also Master’s is needed.Offers quality of services agrees with government regulations, and they are also consulted by them, medical professionals.Dire ctor of EpidemiologyHave the responsibility to determine the cause of a disease as well as health problems providing protection against further recurrence.Industrial waste directorThey focus on keeping the society clean to public health is safe. They ensure that the public employees do their work of collecting the garbage to keep the community cleanRadiation safety specialistThey offer facilities related to public health in dealing with environmental laws. This individual ensures that hazardous materials are kept safe to prevent accidents (Tommy 1).

Unusual Presentation of Ewing’s Sarcoma

Unusual Presentation of Ewing’s Sarcoma D.V.Prasad1, Sanjay Mulay2, Krishna Badgire 3, *Abhinav S.Jadhav4, Deepak Datrange5, Sagar Jawale6, Arun alex7 ABSTRACT: Ewing’s sarcoma is a highly malignant, round cell neoplasm of uncertain origin. It is the sixth most common malignant tumor of bone. It must be distinguished from chronic osteomyelitis and other malignant round cell tumors like lymphoma, metastatic neuroblastoma and small cell osteosarcoma. Most patients are between 10 to 25years old; rarely patients are younger than age 5 years and older than age 40 years. We report a 55 years female who presented with swelling over right shoulder with pain and inability to move right shoulder later diagnosed as Ewing’s sarcoma of proximal part of humerus right side. The earlier diagnosis at this age may help in better management of the condition and prevent further complications and have better prognosis. KEY WORDS: Ewing’s sarcoma, Primitive neuroectodermal tumor (PNET), Ewing family of tumors (EFT), round cell tumor. INTRODUCTION: Ewing’s sarcoma is a highly malignant, round cell neoplasm of uncertain origin. It is the sixth most common malignant tumor of bone [1]. Most patients are between 10 to 25years old; rarely patients are younger than age 5 years and older than age 40 years. The present report is about rare presentation of Ewing’s sarcoma in a 55 years old female who presented with swelling over right shoulder with severe pain and inability to move right shoulder. CASE REPORT: A55 years old female, housewife, was presented with progressive swelling over right shoulder and difficulty in shoulder movements. Swelling was accompanied with severe pain which increased gradually over a period of 6 months. On examination, she was an average built female with swelling over right shoulder and upper part of right arm. Swelling was of 25x20cm size. It was a solitary swelling with local rise of temperature over swelling. Swelling was tender and variable in consistency. It was a non-mobile swelling. Redness and prominent superficial veins were visible over swelling over right shoulder and upper part of arm (Fig.1). Her hemoglobin levels were decreased and she had elevated erythrocyte sedimentation rate (ESR). Her renal function tests and liver function tests were towards lower normal range. X-ray right shoulder with arm shows round lytic lesion in head and upper part of humerus (Fig.2). MRI of right shoulder joint was suggestive of a 8.76.76.5 cm well defined, lobulated, expansile, lytic, lesion involving head and proximal shaft of right humerus, causing thinning and erosion of the cortex with breach at few places and narrow zone of transition, adjacent soft tissue extensions with edema and moderate right shoulder joint effusion. These findings are suggestive of Neoplastic mass involving proximal humerus with pathological fractures (Fig. 3) Histopathology report shows sheets of small round cells with hyperchromatic nuclei, condensed chromatin and scanty eosinophilic cytoplasm with vaculisations with unremarkable bony trabeculae (Fig.4). Immuno-histochemistry is suggestive of Vimentin, CD99, S 100 positive and AE1/AE3 focally positive. Cytology report was suggestive of cytomorphological features positive for malignancy (Fig.5). Fig. 1: Clinical photograph of patient showing right shoulder swelling. Fig.2:X-ray right shoulder showing round lytic area in upper end of humerus. Fig. 3: MRI right shoulder T1W,T2W and STIR images showing expansile, lobulated, lytic lesion involving head and proximal part of humerus. Fig.4: Microscopic picture (40X) showing sheets of small round cells with hyperchromatic nuclei, condensed chromatin and scanty eosinophilic cytoplasm. Fig.5: Cytology report showing cytomorphological features positive for malignancy DISCUSSION: In 1918 Arthur Purdy Stout described a tumor composed of small round cells with rosettes in Ulnar nerve [2], later on it became known as Primitive neuroectodermal tumor (PNET). James Ewing described a tumor of diaphysis of long bones composed of undifferentiated cells and the tumor was radiosensitive [3]. Earlier Ewing’s sarcoma (ES) PNET were described as two separate entities, but in 1975 Angervall and Enzinger described extraskeletal tumor resembling to ES [4]and Jaffe et al. wrote an article on â€Å"the neuroectodermal tumor of bone† in 1984 [5]. Now it is known that ES and PNET show similar translocations and are considered to be ends of histological spectrum of Ewing’s family of tumors (EFT). Analysis of molecular techniques not only provided better understanding of biology but also help in developing better techniques in diagnosis and prospective potential treatment. Epidemology: EFT comprises 5 to 10 % of total bone tumors and is the 2nd most common tumor of childhood [6]. It occurs predominantly in young adults and children and shows a slight predilection for males [7].75% cases are seen between 10 to 25 years age of life. Youngest case reported so far was of 4.5 months old [8] and oldest case reported was 61 years old. Infancy cases are to be differentiated from metastatic neurofibroma. Sites: In 55% long bones it is usually diaphyseal lesion but also metaphyseodiaphyseal lesion can be seen. Flat bone (pelvis and ribs) involvement can also be seen. Less common sites of occurance are skull, vertebra and scapula. Presentation of Ewing’s sarcoma: Pain, Swelling and fever are the presenting symptoms. X-ray shows permeative pattern of bone involvement (boundary between uninvolved bone and area of bone destruction and bone is broad, vague imperceptible). All types of periosteal reactions seen like onion peel, moth eaten, honey combed, fine and reticulated [1]. Biopsy Ideally core biopsy is done, if repeated attempts of core biopsy fails open biopsy is done. FNAC not recommended in case of Ewing’s sarcoma. Frozen section studies opted in selected cases only as freezing of tissue distorts the morphology. Fixation of tissue is done in 10% formalin. Inadequate fixation leads to loss of antigen, so inconclusive results on immunohistochemistry and also causes autolysis and degeneration of DNA thus making molecular analysis difficult. Ratio of specimen to formalin is 1:10. Histology: It is prototype of small round cell tumor growth. It is composed of sheets of small cells with increased nuclear to cytoplasm ratio. Cytoplasm is scanty, eosinophilic, and detected by periodic acid Schiff (PAS), contains glycogen and diastase degradable. Occasional rosette formation are seen and frequently undergoes necrosis and residual viable cells show perithetiomatous or perivascular distribution.EFT tumor cells can be large with irregular nuclear membrane and prominent nucleoli [9]. EFT cells show membrane expression of CD99 /MIC 2 on immunohistochemistry [10]. Antibody against FLI-1 is seen in nucleus of tumor cells which is specific for diagnosis of EFT [11]. Tumor cells may show neuron specific enolase (NSE), synaptophysin and s-100 protein. Family of EFT includes -1)non hodgekin’s lymphoma 2)rhabdomyosarcoma 3)synovial sarcoma 4)messenchymal chondrosarcoma 5)desmoplastic small round cell tumor (DSRCT) 6)retinoblastoma. False positive cd99 screening is seen in other cases as well hence CD99, FLI1 and NSE to be positive for diagnosis of EFT/PNET. Molecular genetics: Translocation t (11:22) (q24:q22) is seen in 85 % cases. Fusion of EWS gene on 22q12 with FLI-1 on 11q24 results in chimeric fusion transcript EWS-FLI1 [12]. EWS-FLI1 induces insulin like growth factor (IGF-1). Phospholipase D2 (PLD2) and Protein tyrosine phosphatase 1 (PTPL1) are expressed in increased levels. Thus tumor cells escape from apoptosin and growth inhibition. Therapeutic targets: EWS-FLI1 fusion is to be targeted and split. Monoclonal antibodies against IGF -1 are being tried as it is associated with EFT growth [13] and PLD 2, PTPL1 are other conceivable candidates as both are highly expressed in EFT [14]. Chemotherapy in ES: There is no universally accepted staging. American joint committee on cancer (AJCC) suggests that primary bone or extra skeletal Ewing’s sarcoma may be included with their respective bone or soft-tissue sarcoma staging (STS) systems [15]. Although AJCC staging includes metastatic disease and tumor size greater or less than 8 cm; nodal status and grade are irrelevant for ES because it rarely spreads by lymph nodes and by definition of ES is high grade tumor [15]. Most of centers use presence or absence of metastasis at the time of diagnosis, as main tool for planning the treatment. Prognostic factors: 1) tumor site and size 2) age and gender 3) serum LDH levels ES in distal extremity has better prognosis than proximal extremity. ES in central location (pelvis) has worst prognosis [16] [17] [18]. Tumor volume 100-200ml- large tumor has bad prognosis. Girls have better prognosis than boys [18]. Increased serum LDH levels at time of diagnosis with large tumor with metastatic disease has worse prognosis. Metastasis in lungs alone has prognosis better than metastasis in extra-pulmonary sites. Patient with minimal tumor or no residual tumor after preoperative chemotherapy incline towards better prognosis. Evolution of chemotherapy: Adjuvant therapy: Vincristine + Actinomycin D + Cyclophosphamide (VAC). Intergroup Ewing’s sarcoma study (IESS): VAC + doxorubicin. IESS trial –II demonstrated that intermittent high doses of VAC + doxorubicin was superior to continuous moderate dose therapy with this agents [19].VAC+ doxorubicin alternating with Ifosfamide and Eloposide (IE) has better prognosis. There is no role of dose intensification. Current trend: Alternating cycles of VAC IE every 3 weeks for 48 weeks with local control at 9-12 weeks [20] is to be administered. There is no role of dose compression (decrease in duration of cycles).There is some role of stem cell in preliminary stage of management. Local therapy: Surgical resection with or without limb salvage followed by Radiotherapy and then chemotherapy is given. Chemotherapy remains back bone of the T/t for Ewing’s sarcoma, local T/t with surgery /or radiotherapy has important role in management of ES. The outcome of management is better in localized ES as compared to elusive outcome in metastatic disease or local recurrence. This case is presented in view of rarity to increase suspicion index for the presence of Ewing’s sarcoma. Early detection of Ewing’s sarcoma as chemotherapy and radiotherapy can limit further damage and progression of the disease can be done. REFERENCES: Joseph M. Mirra, Piero Picci: Ewing’s sarcoma In: Bone tumors- clinical, radiologic, and pathologic correlations, volume two, Lea Febiger, Philadelphia, London1989, pp. 1088-1094. Stout AP. A tumor of the ulnar nerve. Proc NY Pathol Soc 1918; 12:2-12. Ewing J. Diffuse endothelioma of bone. Proc NY Pathol Soc 1921; 21:17-24. Angervall L, Enzinger FM. Extraskeletal neoplasm resembling Ewing’s sarcoma. Cancer 1975; 36:240-51. Jaffe R, Santamaria M, Yunis EJ, Tannery NH, Agostini RM Jr, Medina j, era/. The neuroectodermal tumor of bone. Am j Surg Pathol 1984; 8:885-98. Gurney JG, Swensen AR, Bulterys M. Malignant bone tumors. In: Ries LA, etal, editors. Cancer incidence and survival among children and adolescents: United States SEER Program 1975- 1995. Bethesda, MD: National Cancer institute. SEER Program. NIH Pub. No. 99-4649; 1999. p. 99-110. Zamora P, Garcia de Paredes ML, Gonzalez Baron M, Diaz MA, Escobar Y, Ordonez A, et al. Ewings tumor in brothers. An unusual observation. AmJ Clin Oncol 1986; 9:358-60. Kim, T.E., Ghazi G. Atkinson G. ct al.: Ewings sarcoma of a lower extremity in an infant: A therapeutic dilemma. Cancer, 5c: 187, 1986. Nascimento AG, Unii KK, Pritchard DJ, Cooper KL, Dahlin DC. A clinicopathologic study of 20 cases of large-cell (atypical) Ewings sarcoma of bone. AmJ Surg Pathol 1980; 4:29-36. Khoury JD. Ewing sarcoma family of tumors. Adv Anat Pathol 2005; 12:212-20. Nilsson G, Wang M, Wejde J, Kreicbergs A, Larsson O. Detection of EWS/FL1-1 by immunostaining. An adjunctive tool in diagnosis of Ewing’s sarcoma and primitive neuroectodermal tumour on cytological samples and paraffin-embedded archival material. Sarcoma 1999; 3:25-32. Delattre O, Zucman J, Plougastel B, Desmaze C, MelotT, Peter M, et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 1992; 359:162-5. Ludwig JA. Ewing sarcoma: Historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future. Curr Opin Oncol 2008; 20:412-8. Abaan OD, Levenson A, Khan O, Furth PA, Uren A, Toretsky JA. PTPL1 is a direct transcriptional target of EWS-FL11 and modulates Ewing’s Sarcoma tumorigenesis. Oncogene 2005; 24:2715-22. Greene FL, Page DL, Fleming ID , A. Fritz, C.M Balch, D.G. Haller et al, eds. AJCC cancer staging Manual. 6th ed. New York, NY: Springer; 2002. Rodriguez –Galindo C, Liu T, Krasin MJ, Wu J, Billups CA, Daw NC, et al. Analysis of prognostic factors in Ewing’s sarcoma family of tumors: review of St. Jude children’s research hospital studies cancer 2007; 1 10:375-84. Cotterill SJ, Ahrens S, Paulussen M, Jurgens HF, Voute PA, Gadner H et al. Prognostic factors in Ewing’s tumor of bone: analysis of 975patient from the European intergroup cooperative Ewing’s sarcoma study group. J clin oncol 2000; 18:3108-14. Bacci G, Longhi A, Ferrari S, Mercuri M, Versari M, Bertoni F. Prognostic factors in non-metastatic Ewing’s sarcoma tumor of bone: An analysis of 579 patients treated at a single at a single institution with adjuvant or neo-adjuvant chemotherapy between 1972 and 1998.Acta oncol 2006; 45:469-75. Burgert EO Jr, Nesbit ME , Garnsey LA , Gehan EA, Herrmann J, Vietti TJ, et al. Multimodal therapy for management of non-pelvic , localized Ewing’s sarcoma of bone :intergroup study IESS-II. J Clin Oncol 1990; 8:1514-24. Granowetter L, Womer R, Devidas M, Karlio M, Wang C, Bernstein M, et al. Dose –intensified compared with standard chemotherapy for non-metastatic Ewing’s sarcoma family of tumors: a children’s oncology group study. J clin oncol 2009; 27:2536-41.

Deforestation and its Effect on our Environment Today

DeforestationDeforestation is the operation of cut plants and trees because of fuel and architecture expanding and other reasons. Forests are cut down for many reasons. This essay will describe the causes and effects of deforestation, and how can we solve this problem.There are many causes of the deforestation. Firstly, Agricultural expansion, large scale agriculture is the main economic factor behind deforestation. Another factor which is Logging for Timber logging especially illegal logging, is a major cause of deforestation. Moreover, road construction is the infrastructure development that contributes most to deforestation because roads encourage immigration and the spread of agriculture into forests, particularly in remote areas where property rights are unclear. What's more, is the firewood collection, one third of the world’s population uses biomass fuels, mainly firewood, to cook and to heat their homes, together with population growth, this can have a devastating effe ct on forests in poor countries.Deforestation effect on our environment deeply today. Deforestation resulted in Climate Change, when deforestation occurs, many of the trees are burnt, which resulted in releasing the carbon that is stored in them as carbon dioxide. This leads to greater concentrations of carbon dioxide in the atmosphere. Therefore, the climate will change which cause the global warming. Furthermore, When forests are cut down, this regulation of the flow of water is disrupted, which leads to alternating periods of flood and then drought in the affected area.What then should be recommended as solutions to these problems? For every tree that is cut, three, not two should be planted in its case. We have reached such a critical point that to prevent the desertification so we need to plant more trees.In brief, deforestation is a warning to the worldwide life. It has become a huge concern in today's life. Deforestation can be solved only if everyone cooperate with each othe r and stop people from cutting these forests. Remember you can make a change and influence the people around you to save our beautiful planet. Also, Recycling is an option for the richer countries.